Mr. Khanh said, when his wife was pregnant with her first child, the whole family was very happy.After 9 months and 10 days, his wife successfully overcome.The baby was born very loudly, ruddy.However, until the 3rd day after birth, when the child is breastfeeding, he just goes away, pale.His family took his son to the hospital, the doctor shook his head to inform him that he had died.

The shock of losing children was so unexpected that both him and his wife could not believe.It took a long time for him and his wife to calm down and decided to get pregnant for the second time. This time, the child was born healthy.But 3 days after birth, the child is cyanosis while breastfeeding.When I took my child to the hospital, I died.

Losing 2 children for unknown reasons for Mr. Khanh and his wife did not dare to give birth.Whenever anyone mentioned the children, Mr. Khanh and his wife were pleased.

"I'm afraid if I give birth to the third time, after 3 days my child will die, my husband and I can't stand it", "Mr. Khanh said.

In order to decipher why the child was born only for 3 days and then left his parents, Mr. Khanh and his wife decided to go to the fertile support.

"A child who is like that is doubtful that the reason, that reason but both of them, our husband and wife decided to see a doctor to find the cause", "Mr. Khanh shared.

Mr. Khanh and his wife went to the post office hospital.Reproductive results show that both husband and wife are normal.However, the gene and chromosomes of Mr. Khanh and his wife showed that the couple carrying the diving gene disordered the Urea metabolism (UCD).Both husband and wife were very surprised because they were healthy before.

Explained by the doctor, Mr. Khanh and his wife screened the embryo and made IVF.After that, they had a completely healthy son, not carrying the disease gene.

The case of Mr. Khanh's family is one of many couples with a disease gene that has a healthy child thanks to IVF.

How dangerous genetic metabolism disorders?

MSc Trinh Van Du, Reproduction Support Center, Post HospitalIt is said that congenital metabolic disorders are one of the dangerous diseases, causing high mortality in babies.In many cases, it is not detected early, although not fatal, causing serious consequences in the development of children.

Genetic metabolic disorders are a disease associated with rare genetic factors in children, mostly caused by mutations that encrypt genes for enzymes, enzyme deficiency, or make enzymes inactive.This leads to abnormal changes in the synthesis cycles or degeneration of substances in the body, thereby forming abnormal products that cause cell poisoning, causing impaired organ function, evenChi is death for children.

According to Dr. Du, genetic metabolic disorders are transmitted to the next generation in the form of genetic genetic divers on normal chromosomes.People with inheritance of genetic disease from both parents are good people carrying the disease gene.

As in the case of Mr. Khanh's family, the couple is a good person carrying a disease gene.This means that parents only carry a disease -causing allele, the amount of enzymes in the blood is still sufficient so it does not manifest clinical.Meanwhile, the child is ill because of carrying 2 diseased alleles from both parents, so he cannot produce enough enzymes and manifest the disease.

The rate of giving birth to congenital metabolic disorders is 25% per once if both parents are good people carrying the disease gene.Common genetic metabolic disorders are:

- Organic acid metabolism disorders;

- Carbohydrate metabolic disorders;

- Fatty acid metabolism disorders;

- Purine and pyrimidine metabolic disorders.

According to experts, it is necessary to think of genetic genetic genes when there are one of the following risk factors: the family has one or more deaths of unknown causes;Children with mental retardation, unknown exercise.

When suspecting that the couple carrying genetic genes need to go to the clinic early for advice on screening to have healthy children.

Screening gene disease to have healthy children

Mr. Tran Hung Manh, Director of Post HospitalIt is said that genetic diseases have been recorded in the community for thousands of years and usually will be considered "incurable".Genetic disease is difficult to be detected by common methods caused by good individuals carrying genes that may be healthy, living and normal labor.However, these couples are at risk of giving birth to infected babies.

Genetic disease is a burden on health, finance and psychology for people with the disease, the family and the burden for the health sector, for the whole community.

According to Mr. Manh, many cases of disease or genetic carriers such as congenital hemolysis (thalassemia), hemorrhoids (hemophilia), Duchenne muscle dysplasia, musculoskeletis, metabolic disorders ... when genetic screeningImplementation of in vitro fertilization will have healthy children.